BiologicalActivity
MixedI1imidazolinereceptorandα2-adrenergicagonist;displays40-foldhigheraffinityforI1receptorsversusα2-adrenoceptors.Centrallyactingantihypertensiveagent.
CompoundLibraries
MoxonidinehydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 278.14 |
| Formula | C9H12ClN5O.HCl |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 75536-04-8 |
| PubChemID | 11231255 |
| InChIKey | ZZPAWQYZQVUVHX-UHFFFAOYSA-N |
| Smiles | Cl.COC1=NC(C)=NC(Cl)=C1NC1=NCCN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.81 | 100 | |
| ethanol | 27.81 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight278.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.6mL | 17.98mL | 35.95mL |
| 5mM | 0.72mL | 3.6mL | 7.19mL |
| 10mM | 0.36mL | 1.8mL | 3.6mL |
| 50mM | 0.07mL | 0.36mL | 0.72mL |
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