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Tocris试剂采购 Tocris Bioscience公司代理生物计划,Tocris/NBI 27914 hydrochloride/1591/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城
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Tocris/NBI 27914 hydrochloride/1591/10/10 mg
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Tocris/NBI 27914 hydrochloride/1591/10/10 mg
品牌 / 
Tocris
货号 / 
1591/10
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4000-520-616
Description:Selectivenon-peptideCRF1antagoNIST
ChemicalName:5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediaminehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective,non-peptidecorticotropin-releasingfactor1(CRF1)receptorantagonist(Ki=1.7nM);hasnoactivityatCRF2receptors.Blocksbehavioralseizuresinvivo.

CompoundLibraries

NBI27914hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt470.66
FormulaC18H20Cl4N4.HCl
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber1215766-76-9
PubChemID45073446
InChIKeyCPMGENCTAWBLNW-UHFFFAOYSA-N
SmilesCl.CCCN(CC1CC1)C1=C(Cl)C(NC2=C(Cl)C=C(Cl)C=C2Cl)=NC(C)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.42100
ethanol43.42100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight470.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.12mL10.62mL21.25mL
5mM0.42mL2.12mL4.25mL
10mM0.21mL1.06mL2.12mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet