Tocris经销商/代理商 Tocris Bioscience一级代理,Tocris/NECA/1691/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/NECA/1691/50/50 mg

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Tocris

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1691/50

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4000-520-616

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Description:HighaffinityadenosinereceptoragoNIST

AlternativeNames:5'-N-Ethylcarboxamidoadenosine

ChemicalName:1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highaffinityadenosinereceptoragonist(K_ivaluesare6.2,14,and20nMforhumanA₃,A₁andA_2Areceptorsrespectively;EC₅₀=2.4μMforhumanA_2B).Inhibitsplateletaggregationandiscentrallyactiveinvivo.

CompoundLibraries

NECAisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	308.3
Formula	C₁₂H₁₆N₆O₄
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	35920-39-9
PubChemID	448222
InChIKey	JADDQZYHOWSFJD-FLNNQWSLSA-N
Smiles	O[C@@H]1[C@@H]([C@](NCC)=O)O[C@@H](N2C=NC3=C2N=CN=C3N)[C@@H]1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	12.33	40

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight308.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.24mL	16.22mL	32.44mL
5mM	0.65mL	3.24mL	6.49mL
10mM	0.32mL	1.62mL	3.24mL
50mM	0.06mL	0.32mL	0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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