Tocris代理，产品目录 Tocris Bioscience经销商/代理商,Tocris/NIBR 189/5203/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/NIBR 189/5203/10/10 mg

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Tocris

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5203/10

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Description:PotentandselectiveEBI2(GPR183)receptorantagoNIST

ChemicalName:(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveEBI2(GPR183)receptorantagonist(IC₅₀valuesare11and15nMforhumanandmouseEBI2receptorsrespectively).ExhibitsselectivityforEBI2overapanelofotherreceptors,enzymesandtransporters.Blocksoxysterol-inducedmigrationofU937monocytecells.Orallybioavailable.

TechnicalData

M.Wt	429.31
Formula	C₂₁H₂₁BrN₂O₃
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1599432-08-2
PubChemID	36295259
InChIKey	OFHXXBRBGWUOHR-NYYWCZLTSA-N
Smiles	BrC1=CC=C(/C=C/C(N2CCN(C(C3=CC=C(OC)C=C3)=O)CC2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	42.93	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight429.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.33mL	11.65mL	23.29mL
5mM	0.47mL	2.33mL	4.66mL
10mM	0.23mL	1.16mL	2.33mL
50mM	0.05mL	0.23mL	0.47mL

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