Tocris试剂产品信息 Tocris Bioscience报价单,Tocris/NNC 63-0532/1780/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/NNC 63-0532/1780/10/10 mg

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Tocris

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1780/10

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4000-520-616

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Description:Potentnon-peptideNOPagoNIST;brainpenetrant

ChemicalName:8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-aceticacid,methylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentnon-peptideagonistfortheNOPreceptor(EC₅₀=305nM,K_i=7.3nM);~12-foldselectiveoverotherreceptors.Centrallyactivefollowingsystemicadministrationinvivo.

CompoundLibraries

NNC63-0532isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	443.54
Formula	C₂₇H₂₉N₃O₃
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	250685-44-0
PubChemID	3906780
InChIKey	DSEIKQVUTKGLGT-UHFFFAOYSA-N
Smiles	COC(=O)CN1CN(C2=CC=CC=C2)C2(CCN(CC3=CC=C4C=CC=CC4=C3)CC2)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	22.18	50
	ethanol	2.22	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight443.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.25mL	11.27mL	22.55mL
5mM	0.45mL	2.25mL	4.51mL
10mM	0.23mL	1.13mL	2.25mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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