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Tocris/Ogerin/5722/10/10 mg

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Tocris

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5722/10

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4000-520-616

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Description:SelectivepositiveallostericmodulatoratGPR68

ChemicalName:2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivepositiveallostericmodulatoratGPR68(pEC₅₀=6.83).ExhibitsselectivityforGPR68over58otherGPCRs.Attenuatescontextual-basedfearmemoryinmice.

TechnicalData

M.Wt	307.35
Formula	C₁₇H₁₇N₅O
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1309198-71-7
PubChemID	56707820
InChIKey	MDGIEDNDSFMSLP-UHFFFAOYSA-N
Smiles	NC1=NC(NCC2=CC=CC=C2)=NC(C3=CC=CC=C3CO)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	30.73	100
	ethanol	6.15	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight307.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.25mL	16.27mL	32.54mL
5mM	0.65mL	3.25mL	6.51mL
10mM	0.33mL	1.63mL	3.25mL
50mM	0.07mL	0.33mL	0.65mL

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