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Description:SelectivepositiveallostericmodulatoratGPR68
ChemicalName:2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
SelectivepositiveallostericmodulatoratGPR68(pEC50=6.83).ExhibitsselectivityforGPR68over58otherGPCRs.Attenuatescontextual-basedfearmemoryinmice.
TechnicalData
M.Wt | 307.35 |
Formula | C17H17N5O |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1309198-71-7 |
PubChemID | 56707820 |
InChIKey | MDGIEDNDSFMSLP-UHFFFAOYSA-N |
Smiles | NC1=NC(NCC2=CC=CC=C2)=NC(C3=CC=CC=C3CO)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.73 | 100 | |
ethanol | 6.15 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight307.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.25mL | 16.27mL | 32.54mL |
5mM | 0.65mL | 3.25mL | 6.51mL |
10mM | 0.33mL | 1.63mL | 3.25mL |
50mM | 0.07mL | 0.33mL | 0.65mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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