Tocris试剂产品信息 Tocris Bioscience抗体品牌,Tocris/Oleanolic acid/6026/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Oleanolic acid/6026/50/50 mg

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Tocris

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6026/50

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4000-520-616

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Description:SelectiveGPBAreceptor(TGR5)partialagoNIST

ChemicalName:(3β)-3-Hydroxyolean-12-en-28-oicacid

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPBAreceptor(TGR5)partialagonist(EC₅₀=2.25μM;72%efficacy).DisplaysnoactivityatFXR.Alsoinhibitsproteinphosphate1B(PTP1B)andglycogenphosphorylase.SuppressescellproliferationandincreasesapoptosisinT24bladdercancercells.Antidiabetic,antihyperglycaemic,antitumorandhepatoprotective.

TechnicalData

M.Wt	456.7
Formula	C₃₀H₄₈O₃
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	508-02-1
PubChemID	10494
InChIKey	MIJYXULNPSFWEK-GTOFXWBISA-N
Smiles	[H][C@@]12CC(C)(CC[C@]1(C(O)=O)CC[C@@]3(C2=CC[C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@@]34C)[H])C)O)C)[H])C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.13	20mMwithgentlewarming
	ethanol	4.57	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.19mL	10.95mL	21.9mL
5mM	0.44mL	2.19mL	4.38mL
10mM	0.22mL	1.09mL	2.19mL
50mM	0.04mL	0.22mL	0.44mL

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BiologicalActivity

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