生命科学Tocris价格优惠美国Tocris Bioscience公司,Tocris/PA 452/5086/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/PA 452/5086/50/50 mg

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Tocris

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5086/50

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4000-520-616

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Description:RXRantagoNIST

ChemicalName:2-[[3-(Hexyloxy)-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl]methylamino]-5-pyrimidinecarboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RXRantagonist(pA₂=7.11).TriggersdissociationofRXRtetramers.AttenuatescellproliferationandinducesapoptosisinMCF-7breastcancercells.

CompoundLibraries

PA452isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	439.59
Formula	C₂₆H₃₇N₃O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	457657-34-0
PubChemID	9803242
InChIKey	JJUUTJCZMGZJDZ-UHFFFAOYSA-N
Smiles	CC1(C)C2=C(C=C(N(C3=NC=C(C(O)=O)C=N3)C)C(OCCCCCC)=C2)C(C)(C)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.96	100
	ethanol	4.4	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight439.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.27mL	11.37mL	22.75mL
5mM	0.45mL	2.27mL	4.55mL
10mM	0.23mL	1.14mL	2.27mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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