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Description:Endogenousplatelet-activatingfactor(PAF)
AlternativeNames:Platelet-activatingfactor
ChemicalName:(7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Endogenousplatelet-activatingfactor(PAF)andligandforPAFreceptors.Producedbyinflammatorycellsandapotentchemoattractantforpolymorphonuclearneutrophils.InducesincreasedvascularpermeABIlity.
TechnicalData
| M.Wt | 523.68 |
| Formula | C26H54NO7P |
| Storage | Desiccateat-20°C |
| CASNumber | 74389-68-7 |
| PubChemID | 108156 |
| InChIKey | HVAUUPRFYPCOCA-AREMUKBSSA-N |
| Smiles | CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 52.37 | 100 | |
| water | 52.37 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight523.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.91mL | 9.55mL | 19.1mL |
| 5mM | 0.38mL | 1.91mL | 3.82mL |
| 10mM | 0.19mL | 0.95mL | 1.91mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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