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Description:HighlyselectiveA2BantagoNIST
ChemicalName:8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
AdenosineA2Breceptorantagonistthatdisplays>17000-foldselectivityoverotheradenosinereceptors(Kivaluesare0.553,>10000,>10000and>10000nMforA2B,A1,A2AandA3receptorsrespectively).
CompoundLibraries
PSB603isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 529.01 |
Formula | C24H25ClN6O4S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1092351-10-4 |
PubChemID | 44185871 |
InChIKey | OVHCTHHFOHMNFV-UHFFFAOYSA-N |
Smiles | O=C(NC2=C1NC(C3=CC=C(S(N4CCN(C5=CC=C(Cl)C=C5)CC4)(=O)=O)C=C3)=N2)N(CCC)C1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 26.45 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight529.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.89mL | 9.45mL | 18.9mL |
5mM | 0.38mL | 1.89mL | 3.78mL |
10mM | 0.19mL | 0.95mL | 1.89mL |
50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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