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Tocris/PSB 603/3198/10/10 mg
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Tocris/PSB 603/3198/10/10 mg
品牌 / 
Tocris
货号 / 
3198/10
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4000-520-616
Description:HighlyselectiveA2BantagoNIST
ChemicalName:8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AdenosineA2Breceptorantagonistthatdisplays>17000-foldselectivityoverotheradenosinereceptors(Kivaluesare0.553,>10000,>10000and>10000nMforA2B,A1,A2AandA3receptorsrespectively).

CompoundLibraries

PSB603isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt529.01
FormulaC24H25ClN6O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1092351-10-4
PubChemID44185871
InChIKeyOVHCTHHFOHMNFV-UHFFFAOYSA-N
SmilesO=C(NC2=C1NC(C3=CC=C(S(N4CCN(C5=CC=C(Cl)C=C5)CC4)(=O)=O)C=C3)=N2)N(CCC)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.4550

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight529.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.89mL9.45mL18.9mL
5mM0.38mL1.89mL3.78mL
10mM0.19mL0.95mL1.89mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet