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Tocris/PSNCBAM-1/5321/10/10 mg
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Tocris/PSNCBAM-1/5321/10/10 mg
品牌 / 
Tocris
货号 / 
5321/10
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4000-520-616
Description:CB1receptornegativeallostericmodulator
ChemicalName:N-(4-Chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]urea
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CB1receptornegativeallostericmodulator(IC50valuesare45and209nMfortheinhibitionofCP55,940andWIN55,212-2respectively).HasnoeffectattheCB2receptor.Decreasesfoodintakeandbodyweightinrats.

CompoundLibraries

PSNCBAM-1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt392.88
FormulaC22H21ClN4O
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber877202-74-9
PubChemID11560249
InChIKeyHDAYFSFWIPRJSO-UHFFFAOYSA-N
SmilesClC1=CC=C(NC(NC2=CC(C3=CC=CC(N4CCCC4)=N3)=CC=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.29100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight392.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.55mL12.73mL25.45mL
5mM0.51mL2.55mL5.09mL
10mM0.25mL1.27mL2.55mL
50mM0.05mL0.25mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet