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Tocris/Pamoic acid disodium salt/4298/50/50 mg

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Tocris/Pamoic acid disodium salt/4298/50/50 mg

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Tocris

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4298/50

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4000-520-616

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Description:GPR35agoNIST

ChemicalName:4,4'-MethyleNEBis(3-hydroxy-2-naphthalenecarboxylicacid)disodiumsalt

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPR35agonist.InducesGPR35internalizationandactivatesERK1/2(EC₅₀valuesare22and65nMrespectively).Mediatesrecruitmentofβ-arrestin2toGPR35.Alsoexhibitsantinociceptiveeffectsinamousemodelofvisceralpain.

TechnicalData

M.Wt	432.33
Formula	C₂₃H₁₄Na₂O₆
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	6640-22-8
PubChemID	2723841
InChIKey	YGLLICRFEVEWOZ-UHFFFAOYSA-L
Smiles	[Na+].[Na+].OC1=C(CC2=C3C=CC=CC3=CC(C([O-])=O)=C2O)C2=CC=CC=C2C=C1C([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	32.42	75
	water	43.23	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight432.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.31mL	11.57mL	23.13mL
5mM	0.46mL	2.31mL	4.63mL
10mM	0.23mL	1.16mL	2.31mL
50mM	0.05mL	0.23mL	0.46mL

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