BiologicalActivity
PotentGPR37L1andGPR37agonist(EC50valuesare5and7nM,respectively).Stimulatessignalingthroughpertussistoxin-sensitiveGproteins.StimulatesERKphosphorylation.Protectsagainstcellularstress.PromotesmyelinlipidsynthesisandprolongscellsurvivalinbothSchwanncellsandoligodendrocytes;neuroprotectiveandglioprotective.
TechnicalData
| M.Wt | 1579.72 |
| Formula | C69H110N16O26 |
| Sequence | TXLIDNNATEEILY (Modifications:Ala-2=D-Ala) |
| Storage | Storeat-20°C |
| CASNumber | 196391-82-9 |
| PubChemID | 16197909 |
| InChIKey | SMUKRAODILXPSW-SRWCCNGVSA-N |
| Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto2mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1579.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.63mL | 3.17mL | 6.33mL |
| 5mM | 0.13mL | 0.63mL | 1.27mL |
| 10mM | 0.06mL | 0.32mL | 0.63mL |
| 50mM | 0.01mL | 0.06mL | 0.13mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。