BiologicalActivity
PositiveallostericmodulatorandallostericagoNISTofthehumancalcium-sensingreceptor(hCaSR).Exhibitscalcimimeticactivity.HastheABIlitytorestorefunctiontohCaSRmutantsthatcausefamilialhypocalciurichypercalcemia(FHH)andneonatalseverehyperparathyroidism(NSHPT).Exertsasuppressiveeffectonparathyroid(PT)hormonesecretion;inhibitsPTcellproliferationinratswithrenalinsufficiency.
CompoundLibraries
R568hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 340.29 |
| Formula | C18H22ClNO.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 177172-49-5 |
| PubChemID | 158796 |
| InChIKey | YJXUXANREVNZLH-PFEQFJNWSA-N |
| Smiles | ClC(C=CC=C2)=C2CCCN[C@H](C)C1=CC=CC(OC)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.03 | 100 | |
| ethanol | 34.03 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight340.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.94mL | 14.69mL | 29.39mL |
| 5mM | 0.59mL | 2.94mL | 5.88mL |
| 10mM | 0.29mL | 1.47mL | 2.94mL |
| 50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。