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Description:PotentNPFFreceptoragoNIST
BIOLOGicalActivityTechnicalDataDatasheetsReferences
BiologicalActivity
PotentendogenousNPFFreceptoragonist(EC50valuesare0.0011and29nMforNPFF2andNPFF1,respectively).Attenuatescontractilefunctionofisolatedratandrabbitcardiacmyocytes.Reducesheartrate,strokevolume,ejectionfractionandcardiacoutput,andincreasesplasmaprolactinlevelsinrats.GnIHhomolog.
TechnicalData
| M.Wt | 1428.72 |
| Formula | C67H101N19O14S |
| Sequence | MPHSFANLPLRF (Phe-12=C-terminalamide) |
| Storage | Storeat-20°C |
| CASNumber | 311309-25-8 |
| PubChemID | 71462794 |
| InChIKey | STXUPUZSJMRDJT-IWPKOFGPSA-N |
| Smiles | [H]N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1428.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.7mL | 3.5mL | 7mL |
| 5mM | 0.14mL | 0.7mL | 1.4mL |
| 10mM | 0.07mL | 0.35mL | 0.7mL |
| 50mM | 0.01mL | 0.07mL | 0.14mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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