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Description:Selective,highaffinity5-HT2BantagoNIST
AlternativeNames:MT500
ChemicalName:4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinaminehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Highaffinity5-HT2Breceptorantagonist(pKi=9.5).Displays1000-foldselectivityfor5-HT2BwithgoodbioavailABIlity.
TechnicalData
| M.Wt | 317.79 |
| Formula | C17H16FN3.HCl |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 199864-86-3 |
| PubChemID | 9905058 |
| InChIKey | MKJPYBJBPRFMHL-UHFFFAOYSA-N |
| Smiles | FC1=C(C=CC=C2)C2=C(C3=CC(C(C)C)=NC(N)=N3)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.78 | 100 | |
| ethanol | 31.78 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight317.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.15mL | 15.73mL | 31.47mL |
| 5mM | 0.63mL | 3.15mL | 6.29mL |
| 10mM | 0.31mL | 1.57mL | 3.15mL |
| 50mM | 0.06mL | 0.31mL | 0.63mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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