BiologicalActivity
Potentandselectiveantagonistforthemineralocorticoidreceptor(MR).Inhibitsaldosteroneproductionandsecretion,andselectivelydecreasesex-vivoMRbindinginthehippocampusofadrenalectomisedrats.Alsodecreasesbloodpressureinfemaleratsfollowingcentraladministrationinvivo.
TechnicalData
| M.Wt | 440.66 |
| Formula | C25H37O4K |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 76676-34-1 |
| PubChemID | 23677972 |
| InChIKey | HXJITUGMCJCKCE-UYOQDFFISA-M |
| Smiles | [K+].[H][C@@]12CC[C@@](O)(CCC([O-])=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](CCC)CC2=CC(=O)CC[C@]12C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.41 | 10 | |
| ethanol | 44.07 | 100 | |
| water | 44.07 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight440.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.27mL | 11.35mL | 22.69mL |
| 5mM | 0.45mL | 2.27mL | 4.54mL |
| 10mM | 0.23mL | 1.13mL | 2.27mL |
| 50mM | 0.05mL | 0.23mL | 0.45mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。