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Description:SelectiveH2antagoNIST
ChemicalName:N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethanediaminehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent,selectiveandcompetitivehistamineH2receptorantagonist(pA2=6.95-7.2).Inhibitsgastricacidsecretioninducedbyhistamine,pentagastrin,bethanecolandfoodinvivo.Alsoinhibitsaspirin-inducedgastriclesions.
TechnicalData
| M.Wt | 350.86 |
| Formula | C13H22N4O3S.HCl |
| Storage | Desiccateat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 66357-59-3 |
| PubChemID | 657344 |
| InChIKey | GGWBHVILAJZWKJ-CHHCPSLASA-N |
| Smiles | Cl[H].CNC(NCCSCC1=CC=C(CN(C)C)O1)=CN(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 8.77 | 25mMwithgentlewarming | |
| ethanol | 8.77 | 25 | |
| water | 17.54 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight350.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.85mL | 14.25mL | 28.5mL |
| 5mM | 0.57mL | 2.85mL | 5.7mL |
| 10mM | 0.29mL | 1.43mL | 2.85mL |
| 50mM | 0.06mL | 0.29mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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