BiologicalActivity
5-HT1B/1Dagonist.Antimigraineagent;attenuateseffectsofCGRPonlightaversioninmice.Orallybioavailable.
CompoundLibraries
RizatriptanbenzoateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 391.47 |
| Formula | C15H19N5.C7H6O2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 145202-66-0 |
| PubChemID | 77997 |
| InChIKey | JPRXYLQNJJVCMZ-UHFFFAOYSA-N |
| Smiles | CN(CCC2=CNC1=CC=C(CN3N=CN=C3)C=C12)C.O=C(C4=CC=CC=C4)O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.57 | 50 | |
| water | 39.15 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight391.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.55mL | 12.77mL | 25.54mL |
| 5mM | 0.51mL | 2.55mL | 5.11mL |
| 10mM | 0.26mL | 1.28mL | 2.55mL |
| 50mM | 0.05mL | 0.26mL | 0.51mL |
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