Tocris试剂采购 Tocris神经传递素,Tocris/Ro 67-7476/4346/10/10 mg,受体,Tocris,Bio-Techne,,10 mg蚂蚁淘商城

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Tocris/Ro 67-7476/4346/10/10 mg

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Tocris

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4346/10

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4000-520-616

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Description:PositiveallostericmodulatorofmGlu₁

ChemicalName:(2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PositiveallostericmodulatorofmGlu₁receptors.Potentiatesglutamate-inducedcalciumrelease(EC₅₀=60.1nMatratmGluR1a).DisplaysnoactivityathumanmGlu₁receptors.

CompoundLibraries

Ro67-7476isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	319.39
Formula	C₁₇H₁₈FNO₂S
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	298690-60-5
PubChemID	32681978
InChIKey	DAEHFYNGSSBGSS-KRWDZBQOSA-N
Smiles	FC(C=C2)=CC=[C@@]2[C@@H]1CCCN1S(C3=CC=C(C)C=C3)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	31.94	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight319.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.13mL	15.65mL	31.31mL
5mM	0.63mL	3.13mL	6.26mL
10mM	0.31mL	1.57mL	3.13mL
50mM	0.06mL	0.31mL	0.63mL

ProductDatasheets

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