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Tocris/S 32212 hydrochloride/4508/10/10 mg
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Tocris/S 32212 hydrochloride/4508/10/10 mg
品牌 / 
Tocris
货号 / 
4508/10
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4000-520-616
Description:5-HT2CinverseagoNIST2antagonist
ChemicalName:1,2-Dihydro-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3H-benz[e]indole-3-carboxamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inverseagonistof5-HT2Creceptors(pKi=8.18athuman5-HT2CINIreceptors).Alsoanantagonistofhumanα2-adrenoceptors.DisplaysnegligIBLeaffinityforα1A-adrenoceptors,histamineH1receptorsandmuscarinicM1receptors.

TechnicalData

M.Wt452.98
FormulaC25H28N4O2.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber847871-78-7
PubChemID11487816
InChIKeyRAKGNVNONBJBSW-UHFFFAOYSA-N
SmilesCN(CC2)CCN2C1=C(OC)C=CC(NC(N3C(C=CC5=C4C=CC=C5)=C4CC3)=O)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO11.3225
water11.3225

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight452.98.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.21mL11.04mL22.08mL
5mM0.44mL2.21mL4.42mL
10mM0.22mL1.1mL2.21mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet