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Tocris/SB 216641 hydrochloride/1242/50/50 mg

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Tocris/SB 216641 hydrochloride/1242/50/50 mg

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Tocris

货号 /

1242/50

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4000-520-616

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Description:Selectiveh5-HT_1BantagoNIST

ChemicalName:N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxADIazol-3-yl)-[1,1'-biphenyl]-4-carboxamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Aselectiveh5-HT_1Bantagonistwithapproximately25-foldselectivityoverh5-HT_1Dandlittleornoaffinityforarangeofotherreceptortypes.

LicensingInformation

SoldwiththepermissionofGlaxoSmithKline

TechnicalData

M.Wt	523.03
Formula	C₂₈H₃₀N₄O₄.HCl
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	193611-67-5
PubChemID	10392025
InChIKey	JPBMDMNORXKGHZ-UHFFFAOYSA-N
Smiles	Cl.COC1=C(OCCN(C)C)C=C(NC(=O)C2=CC=C(C=C2)C2=CC=C(C=C2C)C2=NOC(C)=N2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	26.15	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight523.03.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.91mL	9.56mL	19.12mL
5mM	0.38mL	1.91mL	3.82mL
10mM	0.19mL	0.96mL	1.91mL
50mM	0.04mL	0.19mL	0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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PreparingStockSolutions

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