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Description:Potent,selective5-HT6antagoNIST
ChemicalName:4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentandselective5-HT6receptorantagonist(pKi=8.6);displays>160-foldselectivityoverother5-HTreceptorsubtypes.
LicensingInformation
SoldforresearchpurposesunderagreementfromGlaxoSmithKline
TechnicalData
M.Wt | 523.82 |
Formula | C18H22IN3O3S.HCl |
Storage | Desiccateat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 1216468-02-8 |
PubChemID | 53429667 |
InChIKey | BFGOZFXMAJBFGI-UHFFFAOYSA-N |
Smiles | Cl.COC1=CC=C(NS(=O)(=O)C2=CC=C(I)C=C2)C=C1N1CCN(C)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 26.19 | 50 | |
water | 5.24 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight523.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.91mL | 9.55mL | 19.09mL |
5mM | 0.38mL | 1.91mL | 3.82mL |
10mM | 0.19mL | 0.95mL | 1.91mL |
50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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