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Tocris/SB 258585 hydrochloride/1961/50/50 mg
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Tocris/SB 258585 hydrochloride/1961/50/50 mg
品牌 / 
Tocris
货号 / 
1961/50
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Description:Potent,selective5-HT6antagoNIST
ChemicalName:4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselective5-HT6receptorantagonist(pKi=8.6);displays>160-foldselectivityoverother5-HTreceptorsubtypes.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline

TechnicalData

M.Wt523.82
FormulaC18H22IN3O3S.HCl
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber1216468-02-8
PubChemID53429667
InChIKeyBFGOZFXMAJBFGI-UHFFFAOYSA-N
SmilesCl.COC1=CC=C(NS(=O)(=O)C2=CC=C(I)C=C2)C=C1N1CCN(C)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.1950
water5.2410

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight523.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.91mL9.55mL19.09mL
5mM0.38mL1.91mL3.82mL
10mM0.19mL0.95mL1.91mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet