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Description:Selective5-ht5aantagoNIST
ChemicalName:N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamidedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selective5-ht5areceptorantagonist(pKivaluesare8.3,<6.0,<6.0,<6.0,<5.5and<5.5for5-ht5a,5-HT1B/D,5-HT2A,5-HT2C,5-HT1Aand5-HT7receptorsrespectively).
LicensingInformation
SoldforresearchpurposesunderagreementfromGlaxoSmithKline
TechnicalData
| M.Wt | 584.66 |
| Formula | C34H45N3O.2HCl |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 864741-95-7 |
| PubChemID | 11983346 |
| InChIKey | QJMKBIHLMPTYTI-UHFFFAOYSA-N |
| Smiles | O=C(CCC4CCCC4)N(CCN(C)C)CC(C=C2)=CC=C2C1=CC=C(CNCCC3=CC=CC=C3)C=C1.Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 14.62 | 25 | |
| ethanol | 5.85 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight584.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.71mL | 8.55mL | 17.1mL |
| 5mM | 0.34mL | 1.71mL | 3.42mL |
| 10mM | 0.17mL | 0.86mL | 1.71mL |
| 50mM | 0.03mL | 0.17mL | 0.34mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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