BiologicalActivity
SelectiveEP1receptorantagonist(IC50=6.7μMforinhibitionof[3H]-PGE2bindingtoEP1transfectedCOScells).
CompoundLibraries
SC19220isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 331.76 |
| Formula | C16H14ClN3O3 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 19395-87-0 |
| PubChemID | 4336830 |
| InChIKey | KNURFLJTOUGOOQ-UHFFFAOYSA-N |
| Smiles | CC(=O)NNC(=O)N1CC2=C(OC3=CC=C(Cl)C=C13)C=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.18 | 100 | |
| ethanol | 8.29 | 25mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight331.76.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.01mL | 15.07mL | 30.14mL |
| 5mM | 0.6mL | 3.01mL | 6.03mL |
| 10mM | 0.3mL | 1.51mL | 3.01mL |
| 50mM | 0.06mL | 0.3mL | 0.6mL |
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ProductDatasheets
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