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Tocris/SDM25N hydrochloride/1410/10/10 mg

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Tocris/SDM25N hydrochloride/1410/10/10 mg

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Tocris

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1410/10

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4000-520-616

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Description:Potent,selectivenon-peptideδantagoNIST;alsoinhibitsdenguevirusreplication

ChemicalName:(4bS,8R,8aS,14bR)-5,6,7,8,14,14b-Hexahydro-7-(2-methyl-2-propenyl)-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diolhydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandhighlyselectivenon-peptideδreceptorantagonist(K_ivaluesare4.7,3800and7900nMforδ,κandμreceptorsrespectively).Moreselectivethannaltrindole(Cat.No.0740).AlsoinhibitsDenguevirusreplication.

CompoundLibraries

SDM25NhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	450.96
Formula	C₂₆H₂₆N₂O₃.HCl
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	342884-71-3
PubChemID	90479789
InChIKey	QLLCUVACGPLGAX-XXCZMEBESA-N
Smiles	O[C@@]24[C@]3([C@@H]7C(N6)=C(C5=C6C=CC=C5)C4)C1=C(O7)C(O)=CC=C1CC2N(CC(C)=C)CC3.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.09	100
	ethanol	45.09	100
	water	4.5	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight450.96.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.22mL	11.09mL	22.17mL
5mM	0.44mL	2.22mL	4.43mL
10mM	0.22mL	1.11mL	2.22mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

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