Tocris试剂采购 Tocris多肽,Tocris/SDZ SER 082 fumarate/1255/50/50 mg,受体,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/SDZ SER 082 fumarate/1255/50/50 mg

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Tocris/SDZ SER 082 fumarate/1255/50/50 mg

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Tocris

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1255/50

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4000-520-616

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Description:Selective5-HT_2B/2CantagoNIST

ChemicalName:(+)-cis-4,5,7a,8,9,10,11,11a-Octahydro-7H-10-methylindolo[1,7-bc][2,6]-naphthyridinefumarate

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective5-HT_2B/2Creceptorantagonistwithlowaffinityfor5-HT_1Areceptors.Inhibits[³H]-mesulerginebindingto5-HT_2CreceptorswithapK_Dof7.8.Inhibits5-HT_2Bmediatedresponsesintheratfundus(pK_B=7.34).

LicensingInformation

SoldwiththepermissionofNovartisPharmaAG

TechnicalData

M.Wt	344.41
Formula	C₁₅H₂₀N₂.C₄H₄O₄
Storage	StoreatRT
CASNumber	1417343-80-6
PubChemID	45073480
InChIKey	DXUZZRDHJMOLTN-MRYVXRNOSA-N
Smiles	C(C=CC(O[H])=O)(O[H])=O.[H][C@@]23[C@@](CCN(C3)C)([H])CN(CC4)C1=C4C=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinwater

Solubility

Solubleto100mMinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight344.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.9mL	14.52mL	29.04mL
5mM	0.58mL	2.9mL	5.81mL
10mM	0.29mL	1.45mL	2.9mL
50mM	0.06mL	0.29mL	0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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