品牌试剂实验Tocris代理 Tocris小分子,Tocris/SMANT hydrochloride/4662/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/SMANT hydrochloride/4662/10/10 mg

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Tocris/SMANT hydrochloride/4662/10/10 mg

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Tocris

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4662/10

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4000-520-616

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Description:InhibitsSmoothened(Smo)accumulation

ChemicalName:N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamidehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofSmoothened(Smo)signalingviaauniquemechanism.InhibitsShh-inducedaccumulationofSmo::EGFPfusionproteinintheprimarycilium(IC₅₀=1.1μM).Inhibitsbothwild-typeSmoandanoncogenicform(SmoM2)withsimilarefficacy.

TechnicalData

M.Wt	375.73
Formula	C₁₆H₂₃BrN₂O.HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	1177600-74-6
PubChemID	2900213
InChIKey	XQESCHFXROUCOQ-UHFFFAOYSA-N
Smiles	BrC1=CC=C(NC(CCN2CC(C)CC(C)C2)=O)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	37.57	100
	ethanol	7.51	20
	water	7.51	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight375.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.66mL	13.31mL	26.61mL
5mM	0.53mL	2.66mL	5.32mL
10mM	0.27mL	1.33mL	2.66mL
50mM	0.05mL	0.27mL	0.53mL

ProductDatasheets

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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