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Tocris/SR 0987/5868/50/50 mg

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Tocris

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5868/50

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Description:Tcell-specificRORγ(RORγt)agoNIST

ChemicalName:2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Tcell-specificRORγ(RORγt)agonist(EC₅₀=800nMinagenereporterassay).InducesIL-17expressionanddecreasesPD-1expressioninTcellsinvitro.

TechnicalData

M.Wt	397.7
Formula	C₁₆H₁₀ClF₆NO₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	303126-97-8
PubChemID	2323435
InChIKey	IZVBONMVWLTLNT-UHFFFAOYSA-N
Smiles	OC(C(F)(F)F)(C(F)(F)F)C1=CC=C(C=C1)NC(C2=C(C=CC=C2)Cl)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.77	100
	ethanol	39.77	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight397.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.51mL	12.57mL	25.14mL
5mM	0.5mL	2.51mL	5.03mL
10mM	0.25mL	1.26mL	2.51mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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