品牌试剂实验Tocris代理 Tocris小分子,Tocris/SR 1078/4874/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/SR 1078/4874/50/50 mg

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Tocris

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4874/50

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4000-520-616

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Description:RORα/γagoNIST

ChemicalName:N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Agonistofretinoicacidreceptor-relatedorphanreceptors(ROR)RORα/γ.IncreasestranscriptionofRORαtargetgenes;thoughttoincreasep53stABIlity.

LicensingInformation

SoldunderlicensefromTheScrippsResearchInstitute.

CompoundLibraries

SR1078isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	431.25
Formula	C₁₇H₁₀F₉NO₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1246525-60-9
PubChemID	17980288
InChIKey	DUXWIYXHHGNUJU-UHFFFAOYSA-N
Smiles	OC(C(F)(F)F)(C(F)(F)F)C(C=C1)=CC=C1NC(C2=CC=C(C(F)(F)F)C=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.12	100
	ethanol	43.12	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight431.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.32mL	11.59mL	23.19mL
5mM	0.46mL	2.32mL	4.64mL
10mM	0.23mL	1.16mL	2.32mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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