Tocris代理，产品目录 Tocris配体,Tocris/SR 9009/5855/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/SR 9009/5855/50/50 mg

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Tocris

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5855/50

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4000-520-616

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Description:Rev-Erbα/βagoNIST

ChemicalName:Ethyl3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Rev-Erbα/βagonist(EC₅₀=710nM;K_d=800nM).AlterscircADIanlocomotoractivityandcoreclockhypothalamicgeneexpressioninmice.Inducesweightlossindiet-inducedobesemice.Brainpenetrant.

TechnicalData

M.Wt	437.94
Formula	C₂₀H₂₄ClN₃O₄S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1379686-30-2
PubChemID	57394020
InChIKey	MMJJNHOIVCGAAP-UHFFFAOYSA-N
Smiles	ClC(C=C1)=CC=C1CN(CC2CCN(C(OCC)=O)C2)CC3=CC=C([N+]([O-])=O)S3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.79	100
	ethanol	43.79	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight437.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.28mL	11.42mL	22.83mL
5mM	0.46mL	2.28mL	4.57mL
10mM	0.23mL	1.14mL	2.28mL
50mM	0.05mL	0.23mL	0.46mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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