BiologicalActivity
Endogenoussecondmessengerinvolvedinthecontrolofcellproliferationandmotility,andCa2+mobilization.Actsasanagonistatsphingosine-1-phosphatereceptors(S1P1-5)andasanactivatorofGPR3,GPR6andGPR12.Effectorsregulatedincludep38MAPkinase,PLC,adenylylcyclase,myosinlightchainphosphataseandfocaladhesionkinase.
TechnicalData
| M.Wt | 379.48 |
| Formula | C18H38NO5P |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 26993-30-6 |
| PubChemID | 5283560 |
| InChIKey | DUYSYHSSBDVJSM-KRWOKUGFSA-N |
| Smiles | O[C@H](/C=C/CCCCCCCCCCCCC)[C@@H](N)COP(O)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight379.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.64mL | 13.18mL | 26.35mL |
| 5mM | 0.53mL | 2.64mL | 5.27mL |
| 10mM | 0.26mL | 1.32mL | 2.64mL |
| 50mM | 0.05mL | 0.26mL | 0.53mL |
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