Tocris产品促销 Tocris Bioscience型号参数规格,Tocris/TC OT 39/4625/10/10 mg,受体,Tocris,Bio-Techne,,10 mg蚂蚁淘商城

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Tocris/TC OT 39/4625/10/10 mg

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Tocris

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4625/10

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4000-520-616

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Description:Potentnon-peptideoxytocinreceptorpartialagoNIST;alsoV_1areceptorantagonist

ChemicalName:(2S)-_N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-2-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thioxomethyl]-1-pyrrolidinecarboxamide

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentnon-peptideoxytocinreceptorpartialagonist(EC₅₀valuesare33nMand850nMfortheoxytocinreceptorandV₂vasopressinreceptorrespectively).AlsoaV_1avasopressinreceptorantagonist(K_i=330nM).Activeinvivoinaratmodelofuterineresponse.

CompoundLibraries

TCOT39isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	600.78
Formula	C₃₂H₄₀N₈O₂S
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	479232-57-0
PubChemID	24776341
InChIKey	PAEBEUZTAPIOIO-UHFFFAOYSA-N
Smiles	O=C(N5[C@H]([C@](N6CCN(C)CCC6)=S)CCC5)NCC(C(C)=C2)=CC=C2C(N1C(C=CC=C3)=C3NC(N(C)N=C4)=C4C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMin1eq.HClandto100mMinDMSO

Solubility

Solubleto100mMin1eq.HClandto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight600.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.66mL	8.32mL	16.65mL
5mM	0.33mL	1.66mL	3.33mL
10mM	0.17mL	0.83mL	1.66mL
50mM	0.03mL	0.17mL	0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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