Tocris产品目录价格 Tocris Bioscience抗体品牌,Tocris/TC-G 1005/5129/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/TC-G 1005/5129/50/50 mg

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Tocris

货号 /

5129/50

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4000-520-616

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Description:PotentandselectiveGPBAreceptor(TGR5)agoNIST

ChemicalName:(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGPBAagonist(EC₅₀=0.72nMforhTGR5).SelectiveforTGR5overFXR(farnesoidXreceptor).IncreasesplasmaGLP-1levelsandreducesbloodglucoseinmice.Orallyavailable.

CompoundLibraries

TC-G1005isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	399.48
Formula	C₂₅H₂₅N₃O₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1415407-60-1
PubChemID	71450251
InChIKey	JQULIQJSYPZQMA-UHFFFAOYSA-N
Smiles	CC1=CC(OC2=CC=NC=C2C(N3C(C=CC=C4)=C4N(C5CC5)CC3)=O)=C(C)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.95	100
	ethanol	39.95	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight399.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.5mL	12.52mL	25.03mL
5mM	0.5mL	2.5mL	5.01mL
10mM	0.25mL	1.25mL	2.5mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

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PreparingStockSolutions

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