Tocris厂家直采，平行进口生命科学Tocris Bioscience价格优惠,Tocris/TCPOBOP/1225/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/TCPOBOP/1225/50/50 mg

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Tocris

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1225/50

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Description:ConstitutiveandrostanereceptoragoNIST

ChemicalName:1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Agonistoftheconstitutiveandrostanereceptor(CAR)(EC₅₀=20nM).InducesactivityofER1cytochromeP450isozymes,NADPH-cytochromecreductase,microsomalepoxidehydrolaseandglutathioneStransferase.Potentmitogen;induceslivercellproliferationinmice.

TechnicalData

M.Wt	402.06
Formula	C₁₆H₈Cl₄N₂O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	76150-91-9
PubChemID	5382
InChIKey	BAFKRPOFIYPKBQ-UHFFFAOYSA-N
Smiles	ClC(C=N3)=CC(Cl)=C3OC(C=C2)=CC=C2OC1=NC=C(Cl)C=C1Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.02	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight402.06.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.49mL	12.44mL	24.87mL
5mM	0.5mL	2.49mL	4.97mL
10mM	0.25mL	1.24mL	2.49mL
50mM	0.05mL	0.25mL	0.5mL

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