Tocris型号参数规格 Tocris Bioscience中国采购,Tocris/TFM-4AS-1/3813/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/TFM-4AS-1/3813/50/50 mg

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Tocris

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3813/50

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Description:Selectiveandrogenreceptormodulator(SARM)

ChemicalName:(1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-Trimethyl-7-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentselectiveandrogenreceptormodulator(SARM)(IC₅₀=30nM).Steroidalcompound.Exhibitslimitedeffectsonreproductivetissuesandsebaceousglands;doesnotrepressAP-1-sensitiveMMP-1reporter.Inhibits5α-reductasetypeIandII(IC₅₀valuesare2and3nMrespectively).

TechnicalData

M.Wt	474.56
Formula	C₂₇H₃₃F₃N₂O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	188589-61-9
PubChemID	10277123
InChIKey	YFBLEKKYWFJKBP-JZFZSVFHSA-N
Smiles	O=C1C=C[C@@]2(C)[C@](CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](NC5=C(C(F)(F)F)C=CC=C5)=O)([H])N1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	4.75	10
	ethanol	4.75	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight474.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.11mL	10.54mL	21.07mL
5mM	0.42mL	2.11mL	4.21mL
10mM	0.21mL	1.05mL	2.11mL
50mM	0.04mL	0.21mL	0.42mL

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