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Description:Retinoicacidanalog;RARagoNIST
AlternativeNames:Ro13-7410
ChemicalName:4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Extremelypotentanalogofretinoicacid,selectivefortheretinoicacidreceptor(RAR)subtype.Enhancesreprogrammingefficiencyinchemicallyinducedpluripotentstemcells(CiPSCs).
TechnicalData
M.Wt | 348.48 |
Formula | C24H28O2 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 71441-28-6 |
PubChemID | 5289501 |
InChIKey | FOIVPCKZDPCJJY-JQIJEIRASA-N |
Smiles | CC(=C/C1=CC=C(C=C1)C(O)=O)C1=CC=C2C(=C1)C(C)(C)CCC2(C)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 3.48 | 10 | |
ethanol | 1.74 | 5mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight348.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.87mL | 14.35mL | 28.7mL |
5mM | 0.57mL | 2.87mL | 5.74mL |
10mM | 0.29mL | 1.43mL | 2.87mL |
50mM | 0.06mL | 0.29mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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