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Description:PotentandselectiveFFA4(GPR120)agoNIST
ChemicalName:4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentFFA4(GPR120)agonist(pEC50valuesare7.36and7.77forhumanandmouseGPR120respectively).SelectiveforGPR120overfreefattyacidreceptors(pEC50=4.19forFFA1;displaysnoactivityatFFA2orFFA3).Cellpermeable.
LicensingInformation
SoldunderlicensefromtheUniversityofSouthernDenmark.
CompoundLibraries
TUG891isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 364.41 |
| Formula | C23H21FO3 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 1374516-07-0 |
| PubChemID | 57522038 |
| InChIKey | LPGBXHWIQNZEJB-UHFFFAOYSA-N |
| Smiles | FC1=CC(COC2=CC=C(CCC(O)=O)C=C2)=C(C3=CC=C(C)C=C3)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 36.44 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight364.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.74mL | 13.72mL | 27.44mL |
| 5mM | 0.55mL | 2.74mL | 5.49mL |
| 10mM | 0.27mL | 1.37mL | 2.74mL |
| 50mM | 0.05mL | 0.27mL | 0.55mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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