Tocris报价单 TOCRIS 4372-10MG,Tocris/Teijin compound 1/3664/50/50 mg,受体,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Teijin compound 1/3664/50/50 mg

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Tocris

货号 /

3664/50

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4000-520-616

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Description:PotentCCR2bantagoNIST

ChemicalName:N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentchemokineCCR2breceptorantagonist(IC₅₀=180nM).PotentlyinhibitscellchemotaxisinducedbyMCP-1(EC₅₀=24nM).

CompoundLibraries

Teijincompound1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	476.32
Formula	C₂₁H₂₁ClF₃N₃O₂.HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	1313730-14-1
PubChemID	56972239
InChIKey	PGUQBBISBKGQDC-GMUIIQOCSA-N
Smiles	O=C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)N[C@@H]1CCN(CC2=CC=C(Cl)C=C2)C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.63	100
	water	4.76	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight476.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.1mL	10.5mL	20.99mL
5mM	0.42mL	2.1mL	4.2mL
10mM	0.21mL	1.05mL	2.1mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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