Tocris试剂产品信息 Tocris Bioscience批发，产品货源,Tocris/BPTU/6078/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/BPTU/6078/50/50 mg

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Tocris

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6078/50

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4000-520-616

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Description:P2Y₁allostericantagoNIST

ChemicalName:N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]urea

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AllostericantagonistofP2Y₁(EC₅₀=0.06-0.3μM).Non-nucleotideligand.Bindsreceptoroutsideofthehelicalbundle.Blocksinhibitionofspontaneouscontractionofratandmousecoloninducedbyelectricalfieldstimulation,nicotineandP2Yagonists.Antithrombotic;reducesplateletaggregation.

TechnicalData

M.Wt	445.43
Formula	C₂₃H₂₂F₃N₃O₃
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	870544-59-5
PubChemID	11510579
InChIKey	AHFLGPTXSIRAQK-UHFFFAOYSA-N
Smiles	CC(C)(C1=C(C=CC=C1)OC2=C(C=CC=N2)NC(NC3=CC=C(C=C3)OC(F)(F)F)=O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.54	100
	ethanol	44.54	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight445.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.25mL	11.23mL	22.45mL
5mM	0.45mL	2.25mL	4.49mL
10mM	0.22mL	1.12mL	2.25mL
50mM	0.04mL	0.22mL	0.45mL

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