BiologicalActivity
AselectivegroupIIImGlureceptorantagonist(apparentKdvaluesare5.1and488μMforgroupIIIandgroupIImGlureceptorsrespectively;IC50>1mMforgroupI,NMDA,AMPAandkainatereceptors).
TechnicalData
| M.Wt | 259.2 |
| Formula | C10H14NO5P |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 339526-74-8 |
| PubChemID | 5022489 |
| InChIKey | LLEOLNUKLKCAFG-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)(C)C1=CC=C(P(O)(O)=O)C(C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto100mMin1eq.NaOH |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight259.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.86mL | 19.29mL | 38.58mL |
| 5mM | 0.77mL | 3.86mL | 7.72mL |
| 10mM | 0.39mL | 1.93mL | 3.86mL |
| 50mM | 0.08mL | 0.39mL | 0.77mL |
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