![Tocris/d[Leu<sup>4</sup>,Lys<sup>8</sup>]-VP/3127/1/1 mg](images/201712/1512520078951260693.jpg)
BiologicalActivity
SelectivevasopressinV1Breceptoragonist(Kivaluesare0.16,64,100and3800nMforV1B,oxytocin,V2andV1Areceptorsrespectively).Displaysweakantidiuretic,vasopressorandinvitrooxytocicactivities.
TechnicalData
| M.Wt | 1026.2 |
| Formula | C47H67N11O11S2 |
| Sequence | XYFLNCPKG (Modifications:X=Mpr,Gly-9=C-terminalamide,DisulfidebridgebetweenX-1-Cys-6) |
| Storage | Storeat-20°C |
| CASNumber | 42061-33-6 |
| PubChemID | 44419030 |
| InChIKey | QGZMLGLFLYCDQT-PEAOEFARSA-N |
| Smiles | CC(C)C[C@@H]1NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)NCC(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto2mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1026.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.97mL | 4.87mL | 9.74mL |
| 5mM | 0.19mL | 0.97mL | 1.95mL |
| 10mM | 0.1mL | 0.49mL | 0.97mL |
| 50mM | 0.02mL | 0.1mL | 0.19mL |
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