BiologicalActivity
PositiveallostericmodulatorofmGlu5receptors(EC50=33nM).BindstoasitedistinctfromthatboundbyMPEP(Cat.No.1212).
TechnicalData
| M.Wt | 305.32 |
| Formula | C17H17F2NO2 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 433967-28-3 |
| PubChemID | 2296132 |
| InChIKey | AHCYOTLTLQTPSU-UHFFFAOYSA-N |
| Smiles | O=C(NC2=C(F)C=C(F)C=C2)C1=CC=C(OCCCC)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.53 | 100 | |
| ethanol | 30.53 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight305.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.28mL | 16.38mL | 32.75mL |
| 5mM | 0.66mL | 3.28mL | 6.55mL |
| 10mM | 0.33mL | 1.64mL | 3.28mL |
| 50mM | 0.07mL | 0.33mL | 0.66mL |
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