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Description:Selectiveα2antagoNIST
ChemicalName:17α-Hydroxyyohimban-16α-carboxylicacidmethylesterhydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
α2-adrenoceptorantagonist(pKivaluesare8.52,8.00and9.17forhumanα2A,α2Bandα2Creceptorsrespectively).DiastereomerRauwolscinehydrochloride(Cat.No.0891)alsoavailable.
TechnicalData
| M.Wt | 390.91 |
| Formula | C21H26N2O3.HCl |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 65-19-0 |
| PubChemID | 6169 |
| InChIKey | PIPZGJSEDRMUAW-VJDCAHTMSA-N |
| Smiles | [H][C@]12C4=C(C(C=CC=C5)=C5N4)CCN1C[C@@]3([H])[C@]([C@@H]([C@@](OC)=O)[C@@H](O)CC3)([H])C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 7.82 | 20mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight390.91.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.56mL | 12.79mL | 25.58mL |
| 5mM | 0.51mL | 2.56mL | 5.12mL |
| 10mM | 0.26mL | 1.28mL | 2.56mL |
| 50mM | 0.05mL | 0.26mL | 0.51mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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