BiologicalActivity
AtypicalantipsychoticthatdisplayscombinedSEROtoninanddopaminereceptorantagonism.Displayshighaffinityat5-HT2Areceptorswitha5-HT2A/D2affinityratiogreaterthananyotherclinicallyavailableatypicalantipsychotics(pKivaluesare9.38,8.88,8.69,8.47,8.32,8.14,7.98,7.49,7.33and6.28for5-HT2A,5-HT2C,5-HT1D,5-HT1A,D2,D3,α1,D4,H1andD1receptorsrespectively).
LicensingInformation
SoldforresearchpurposesunderagreementfromPfizerInc.
TechnicalData
| M.Wt | 449.4 |
| Formula | C21H21ClN4OS.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 138982-67-9 |
| PubChemID | 219099 |
| InChIKey | NZDBKBRIBJLNNT-UHFFFAOYSA-N |
| Smiles | O=C2CC1=CC(CCN3CCN(C4=NSC5=C4C=CC=C5)CC3)=C(Cl)C=C1N2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.49 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight449.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.23mL | 11.13mL | 22.25mL |
| 5mM | 0.45mL | 2.23mL | 4.45mL |
| 10mM | 0.22mL | 1.11mL | 2.23mL |
| 50mM | 0.04mL | 0.22mL | 0.45mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。