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Description:α1AagoNIST
ChemicalName:N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamidehydrobromide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentα-adrenoceptoragonistthatisatleast35-foldmorepotentatα1Athanatα1Borα1Dsites.InducesdoseresponseincreasesinspontaneousCa2+transientsinratventricularmyocytesinvitro(EC50=6.9nmol/L).Alsoavailableaspartoftheα1-AdrenoceptorTocriset™.
TechnicalData
| M.Wt | 390.29 |
| Formula | C14H19N3O3S.HBr |
| Storage | Desiccateat+4°C |
| CASNumber | 107756-30-9 |
| PubChemID | 9865178 |
| InChIKey | LRFLWCZMTGTUEP-UHFFFAOYSA-N |
| Smiles | Br.CS(=O)(=O)NC1=C(O)C=CC2=C1CCCC2C1=NCCN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto50mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight390.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.56mL | 12.81mL | 25.62mL |
| 5mM | 0.51mL | 2.56mL | 5.12mL |
| 10mM | 0.26mL | 1.28mL | 2.56mL |
| 50mM | 0.05mL | 0.26mL | 0.51mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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