Tocris抗体，试剂，血清，细胞 Tocris小分子,Tocris/A 943931 dihydrochloride/3753/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/A 943931 dihydrochloride/3753/10/10 mg

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Tocris/A 943931 dihydrochloride/3753/10/10 mg

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Tocris

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3753/10

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Description:PotentandselectiveH₄antagoNIST

ChemicalName:4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivehistamineH₄receptorantagonist(pK_ivaluesare7.15and8.12athumanandratreceptorsrespectively).Blocksinflammationinaperitonitismousemodelanddisplaysefficacyininflammatorypainandneuropathicpainmodels.

TechnicalData

M.Wt	368.31
Formula	C₁₇H₂₁N₅.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1227675-50-4
PubChemID	56972240
InChIKey	ISYUFRNZHUOGLA-CURYUGHLSA-N
Smiles	NC1=NC(N4C[C@H](N)CC4)=C2C(C(C=CC=C3)=C3CCC2)=N1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.83	100
	water	36.83	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight368.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.72mL	13.58mL	27.15mL
5mM	0.54mL	2.72mL	5.43mL
10mM	0.27mL	1.36mL	2.72mL
50mM	0.05mL	0.27mL	0.54mL

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