Tocris配体 TOCRIS 4372-10MG,Tocris/ABP 688/5229/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ABP 688/5229/50/50 mg

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Tocris

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5229/50

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4000-520-616

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Description:HighaffinityhumanmGlu₅receptorantagoNIST

ChemicalName:3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-oneO-methyloxime

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityhumanmGlu₅receptorantagonist(K_i=1.7nM).Inhibitsglutamate-inducedcalciumreleasefromL(tk-)cellsexpressinghumanmGlu₅receptors(IC₅₀=2.3nM).

TechnicalData

M.Wt	240.3
Formula	C₁₅H₁₆N₂O
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	924298-51-1
PubChemID	11481862
InChIKey	CNNZLFXCUQLKOB-BMRADRMJSA-N
Smiles	CC1=CC=CC(C#CC(CCC2)=C/C2=N/OC)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	12.02	50
	DMSO	24.03	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight240.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	4.16mL	20.81mL	41.61mL
5mM	0.83mL	4.16mL	8.32mL
10mM	0.42mL	2.08mL	4.16mL
50mM	0.08mL	0.42mL	0.83mL

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