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Tocris/AC 261066/4046/10/10 mg
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Tocris/AC 261066/4046/10/10 mg
品牌 / 
Tocris
货号 / 
4046/10
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4000-520-616
Description:RARβ2agoNIST
ChemicalName:4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentRARβ2agonist(pEC50=8.1).SelectiveoverRARβ1,RARαandRARγ(pEC50valuesare6.4,6.2and6.3respectively).MorepotentandorallyavailablethanAC55649(Cat.No.2436).

CompoundLibraries

AC261066isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt353.41
FormulaC17H20FNO4S
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber870773-76-5
PubChemID11530459
InChIKeyHSAOETBFVAWNRP-UHFFFAOYSA-N
SmilesCC1=C(OCCOCCCC)N=C(C2=CC=C(C(O)=O)C(F)=C2)S1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.34100
ethanol35.34100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight353.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.83mL14.15mL28.3mL
5mM0.57mL2.83mL5.66mL
10mM0.28mL1.41mL2.83mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet